{"id":2324,"date":"2022-06-14T09:00:00","date_gmt":"2022-06-14T07:00:00","guid":{"rendered":"http:\/\/localhost\/?p=2324"},"modified":"2022-09-08T12:03:19","modified_gmt":"2022-09-08T10:03:19","slug":"endo-tools-therapeutics-receives-positive-opinion-from-french-high-authority-on-health-on-forfait-innovation-scheme-to-treat-patients-with-diabetes%ef%bf%bc","status":"publish","type":"post","link":"https:\/\/www.endotools.be\/us-en\/2022\/06\/14\/endo-tools-therapeutics-receives-positive-opinion-from-french-high-authority-on-health-on-forfait-innovation-scheme-to-treat-patients-with-diabetes%ef%bf%bc\/","title":{"rendered":"Endo Tools Therapeutics receives positive opinion from French High Authority on Health on Forfait Innovation scheme to treat patients with diabetes"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2324\" class=\"elementor elementor-2324 elementor-2323\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section 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class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Endo Tools Therapeutics receives positive opinion from French High Authority on Health on Forfait Innovation scheme to treat patients with diabetes<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-70706fb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"70706fb\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b5fca89\" data-id=\"b5fca89\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1d84dcc elementor-align-left elementor-widget elementor-widget-post-info\" data-id=\"1d84dcc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-d9dfd61\" itemprop=\"datePublished\">\n\t\t\t\t\t\t<a href=\"https:\/\/www.endotools.be\/us-en\/2022\/06\/14\/\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>June 14, 2022<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-db3b797 elementor-widget elementor-widget-text-editor\" data-id=\"db3b797\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Following positive opinion, medical devices company plans to request temporary funding to conduct clinical study of its endomina\u00ae device in patients in France with type II diabetes and class I obesity<\/strong><\/p><p><b data-stringify-type=\"bold\">Gosselies, Belgium, June 14, 2022<\/b> \u2013 Endo Tools Therapeutics (ETT), a company developing advanced endoscopic medical devices, today announces that HAS, the French High Authority for Health, has issued a positive opinion to initiate a clinical study of the endomina<b data-stringify-type=\"bold\">\u00ae <\/b>triangulation platform and the TAPES suturing device within the framework of the <i data-stringify-type=\"italic\">Forfait Innovation<\/i> program.<\/p><p><i data-stringify-type=\"italic\">Forfait Innovation<\/i> provides special temporary reimbursement for medical technologies, <i data-stringify-type=\"italic\">in vitro<\/i> diagnostic devices or innovative procedures that are in the early diffusion stage, to allow French patients early access to medical innovations. This reimbursement is conditional on the completion of a study prospectively demonstrating the technology&#8217;s clinical potential. <a class=\"c-link\" tabindex=\"-1\" href=\"https:\/\/solidarites-sante.gouv.fr\/systeme-de-sante-et-medico-social\/recherche-et-innovation\/forfait-innovation\" target=\"_blank\" rel=\"noopener noreferrer\" data-stringify-link=\"https:\/\/solidarites-sante.gouv.fr\/systeme-de-sante-et-medico-social\/recherche-et-innovation\/forfait-innovation\" data-sk=\"tooltip_parent\" data-remove-tab-index=\"true\">So far, only 14 medical devices have been enrolled in the Forfait Innovation program<\/a>.<\/p><p>The next step for ETT is to enter budget discussions with the French Ministry for Solidarity and Health. Upon completion, ETT will work with the 12 French study sites and use the <i data-stringify-type=\"italic\">Forfait Innovation<\/i> financing to conduct a clinical study demonstrating the consequence of weight loss on type II diabetes, a co-morbidity of obesity. The endomina could be reimbursed in France for use in the clinical study and subsequently, during continued access in the ESTIME study centers. The endomina device is a triangulation platform currently indicated in the EU to perform endoscopic gastroplasty orally to reduce the volume of the stomach.<\/p><p>The ESTIME clinical trial will be a prospective, multi-center randomized study on patients with type II diabetes and class I obesity, monitoring them over two years for the potential benefit of the procedure in type II diabetes. The study will be led by Professor Marc Barthet, gastroenterologist, Assistance-Publique H\u00f4pitaux de Marseille (AP-HM) and Professor Anne-Laure Borel, endocrinologist, Grenoble University Hospital (CHU). The study aims to demonstrate that the minimally invasive endomina device has the potential to improve type II diabetes by reducing anti-diabetic medication and even, hypothetically, by delivering type II diabetes remission. The study will assess whether the intervention improves patient\u2019s quality of life and limits a patient\u2019s hospital stay to one night.<\/p><p>\u201cOn approval of the <i data-stringify-type=\"italic\">Forfait Innovation<\/i> funding, we would be able to help patients with type II diabetes and class I obesity gain access to a minimally invasive treatment that could improve type II diabetes and, we hope, might even lead to remission. If confirmed by the study, this has the potential to become a standard-of-care offered when conventional treatments are not sufficient,\u201d said Prof. Borel.<\/p><p>\u201cSupported by life-style counseling, the patient might expect to lose <a class=\"c-link\" tabindex=\"-1\" href=\"https:\/\/gut.bmj.com\/content\/70\/8\/1479\" target=\"_blank\" rel=\"noopener noreferrer\" data-stringify-link=\"https:\/\/gut.bmj.com\/content\/70\/8\/1479\" data-sk=\"tooltip_parent\" data-remove-tab-index=\"true\">clinically meaningful weight<\/a>, which in turn might have a positive clinical outcome on the management of type II diabetes,\u201d Prof. Barthet added.<\/p><p>\u201cESTIME is a landmark clinical study. We are delighted with this positive opinion from the HAS, which will enable ETT to start budgetary discussions related to the ESTIME study,\u201d said Alexandre Chau, CEO of Endo Tools Therapeutics. \u201cETT would like to thank the primary investigators, Prof. Marc Barthet and Prof. Anne-Laure Borel, for their continued dedication and support in receiving this opinion from the French High Authority for Health.\u201d<\/p><p>According to the International Diabetes Federation, approximately 537 million adults (20-79 years) are currently living with diabetes; this number is projected to rise to 643 million by 2030. Type II diabetes is the most common type of diabetes, accounting for around 90% of all diabetes cases. Diabetes caused 6.7 million deaths in 2021.<\/p><p><b data-stringify-type=\"bold\">About Endo Tools Therapeutics<\/b><br>Located in Gosselies, Belgium, Endo Tools Therapeutics S.A. (ETT)\u2019s mission is to develop advanced, incisionless, minimally invasive medical devices for use with standard endoscopes.<br>The company targets indications that cannot be performed with standard gastroscopes, such as endoscopic suturing and tissue approximation. These can be used in a variety of procedures in the digestive tract such as bariatric interventions, Gastroesophageal Reflux Disease (GERD) and Endoscopic Full Thickness Resection (EFTR). Minimally invasive treatments can reduce the length of hospital stays and aim to improve patient comfort. Results of bariatric procedures performed within studies with its soft tissue approximation devices were published in <a class=\"c-link\" tabindex=\"-1\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0016510716304746\" target=\"_blank\" rel=\"noopener noreferrer\" data-stringify-link=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0016510716304746\" data-sk=\"tooltip_parent\" data-remove-tab-index=\"true\"><i data-stringify-type=\"italic\">GIE <\/i>in 2017<\/a>, <a class=\"c-link\" tabindex=\"-1\" href=\"https:\/\/www.thieme-connect.com\/products\/ejournals\/abstract\/10.1055\/a-0630-1224\" target=\"_blank\" rel=\"noopener noreferrer\" data-stringify-link=\"https:\/\/www.thieme-connect.com\/products\/ejournals\/abstract\/10.1055\/a-0630-1224\" data-sk=\"tooltip_parent\" data-remove-tab-index=\"true\"><i data-stringify-type=\"italic\">Endoscopy <\/i>in 2018<\/a> and <a class=\"c-link\" tabindex=\"-1\" href=\"https:\/\/gut.bmj.com\/content\/early\/2020\/10\/27\/gutjnl-2020-322026.info\" target=\"_blank\" rel=\"noopener noreferrer\" data-stringify-link=\"https:\/\/gut.bmj.com\/content\/early\/2020\/10\/27\/gutjnl-2020-322026.info\" data-sk=\"tooltip_parent\" data-remove-tab-index=\"true\"><i data-stringify-type=\"italic\">Gut<\/i> in 2020<\/a>. More than 500 procedures (in the EMEA region) have already been performed with the company\u2019s devices.<\/p><p><a class=\"c-link\" tabindex=\"-1\" href=\"http:\/\/www.endotools.be\/\" target=\"_blank\" rel=\"noopener noreferrer\" data-stringify-link=\"http:\/\/www.endotools.be\" data-sk=\"tooltip_parent\" data-remove-tab-index=\"true\">www.endotools.be<\/a><\/p><p><b data-stringify-type=\"bold\">Press and analysts contact<\/b><br>Andrew Lloyd &amp; Associates<br>Saffiyah Khalique \/ Celine Gonzalez<br><a class=\"c-link\" href=\"mailto:saffiyah@ala.com\" target=\"_blank\" rel=\"noopener noreferrer\" data-stringify-link=\"mailto:saffiyah@ala.com\" data-sk=\"tooltip_parent\" aria-haspopup=\"menu\" aria-expanded=\"false\">saffiyah@ala.com<\/a> \/ <a class=\"c-link\" href=\"mailto:celine@ala.com\" target=\"_blank\" rel=\"noopener noreferrer\" data-stringify-link=\"mailto:celine@ala.com\" data-sk=\"tooltip_parent\" aria-haspopup=\"menu\" aria-expanded=\"false\">celine@ala.com<\/a><br>UK: 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